1RD9

Cholera Toxin B-Pentamer Complexed With Bivalent Nitrophenol-Galactoside Ligand BV2

Summary for 1RD9

Entry DOI	10.2210/pdb1rd9/pdb
Related	1RCV 1RDP 1RF2
Descriptor	cholera toxin B protein (CTB), 1,3-BIS-([3-(4-{3-[3-NITRO-5-(GALACTOPYRANOSYLOXY)-BENZOYLAMINO]-PROPYL}-PIPERAZIN-1-YL)-PROPYL-AMINO]-CARBONYLOXY)-2-AMINO-PROPANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywords	bivalent, cholera, toxin, pentamer, complex
Biological source	Vibrio cholerae
Cellular location	Secreted: P01556
Total number of polymer chains	5
Total formula weight	64511.97
Authors	Pickens, J.C.,Mitchell, D.D.,Liu, J.,Tan, X.,Zhang, Z.,Verlinde, C.L.,Hol, W.G.,Fan, E. (deposition date: 2003-11-05, release date: 2004-10-26, Last modification date: 2011-07-13)
Primary citation	Pickens, J.C.,Mitchell, D.D.,Liu, J.,Tan, X.,Zhang, Z.,Verlinde, C.L.,Hol, W.G.,Fan, E. Nonspanning bivalent ligands as improved surface receptor binding inhibitors of the cholera toxin B pentamer. Chem.Biol., 11:1205-1215, 2004 Cited by PubMed: 15380181 DOI: 10.1016/j.chembiol.2004.06.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.44 Å)

Structure validation