1R6W

Crystal structure of the K133R mutant of o-Succinylbenzoate synthase (OSBS) from Escherichia coli. Complex with SHCHC

Summary for 1R6W

Entry DOI	10.2210/pdb1r6w/pdb
Related	1FHU 1FHV
Descriptor	o-Succinylbenzoate Synthase, MAGNESIUM ION, 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, ... (4 entities in total)
Functional Keywords	enolase superfamily; tim barrel; capping alpha+beta domain, lyase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	36030.25
Authors	Klenchin, V.A.,Taylor Ringia, E.A.,Gerlt, J.A.,Rayment, I. (deposition date: 2003-10-17, release date: 2003-11-25, Last modification date: 2023-08-23)
Primary citation	Klenchin, V.A.,Taylor Ringia, E.A.,Gerlt, J.A.,Rayment, I. Evolution of Enzymatic Activity in the Enolase Superfamily: Structural and Mutagenic Studies of the Mechanism of the Reaction Catalyzed by o-Succinylbenzoate Synthase from Escherichia coli Biochemistry, 42:14427-14433, 2003 Cited by PubMed: 14661953 DOI: 10.1021/bi035545v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.62 Å)

Structure validation