1QQP

FOOT-AND-MOUTH DISEASE VIRUS/ OLIGOSACCHARIDE RECEPTOR COMPLEX.

Replaces:  1FHP

Summary for 1QQP

• Entry DOI: 10.2210/pdb1qqp/pdb
• Descriptor: PROTEIN (GENOME POLYPROTEIN), 2-O-sulfo-alpha-L-gulopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-gulopyranuronic acid, ... (6 entities in total)
• Functional Keywords: virus, heparan sulphate, virus-receptor interactions/protein-carbohydrate interactions, virus/viral protein, icosahedral virus
• Biological source: Foot-and-mouth disease virus; More
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B-1: Virion (Potential). Protein 3B-2: Virion (Potential). Protein 3B-3: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03305 P03305 P03305 P03305
• Total number of polymer chains: 4
• Total formula weight: 82269.74

Authors

Fry, E.E.,Lea, S.M.,Jackson, T.,Newman, J.W.I.,Ellard, F.M.,Blakemore, W.E.,Abu-Ghazaleh, R.,Samuel, A.,King, A.M.Q.,Stuart, D.I. (deposition date: 1999-05-20, release date: 1999-06-18, Last modification date: 2023-08-16)

• Primary citation: Fry, E.E.,Lea, S.M.,Jackson, T.,Newman, J.W.,Ellard, F.M.,Blakemore, W.E.,Abu-Ghazaleh, R.,Samuel, A.,King, A.M.,Stuart, D.I.; The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.; EMBO J., 18:543-554, 1999; PubMed: 9927414; DOI: 10.1093/emboj/18.3.543

Experimental method

X-RAY DIFFRACTION (1.9 Å)