1QPR

QUINOLINATE PHOSPHORIBOSYLTRANSFERASE (QAPRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH PHTHALATE AND PRPCP

Summary for 1QPR

Entry DOI	10.2210/pdb1qpr/pdb
Descriptor	QUINOLINIC ACID PHOSPHORIBOSYLTRANSFERASE, MANGANESE (II) ION, PHTHALIC ACID, ... (5 entities in total)
Functional Keywords	prtase, de novo nad biosynthesis, prpp, transferase, phosphoribosyltransferase, quinolinic acid, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	6
Total formula weight	183089.80
Authors	Sharma, V.,Grubmeyer, C.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 1998-10-17, release date: 1998-10-21, Last modification date: 2024-02-14)
Primary citation	Sharma, V.,Grubmeyer, C.,Sacchettini, J.C. Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target. Structure, 6:1587-1599, 1998 Cited by PubMed: 9862811 DOI: 10.1016/S0969-2126(98)00156-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation