1QPF

FK506 BINDING PROTEIN (12 KDA, HUMAN) COMPLEX WITH L-709,858

Summary for 1QPF

Entry DOI	10.2210/pdb1qpf/pdb
Related	1FKD 1TCO 1YAT 2FKE
Descriptor	PROTEIN (FK506-BINDING PROTEIN), C32-O-(1-ETHYL-INDOL-5-YL)ASCOMYCIN, heptyl beta-D-glucopyranoside, ... (4 entities in total)
Functional Keywords	immunophilin-drug complex, cis-trans isomerase, peptidyl-prolyl isomerase, isomerase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytosol : P62942
Total number of polymer chains	2
Total formula weight	25821.74
Authors	Becker, J.W.,Rotonda, J. (deposition date: 1999-05-24, release date: 1999-08-16, Last modification date: 2023-08-16)
Primary citation	Becker, J.W.,Rotonda, J.,Cryan, J.G.,Martin, M.,Parsons, W.H.,Sinclair, P.J.,Wiederrecht, G.,Wong, F. 32-Indolyl ether derivatives of ascomycin: three-dimensional structures of complexes with FK506-binding protein. J.Med.Chem., 42:2798-2804, 1999 Cited by PubMed: 10425089 DOI: 10.1021/jm9806042 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation