1QPE

STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS

Summary for 1QPE

Entry DOI	10.2210/pdb1qpe/pdb
Related	1QPC 1QPD 1QPJ
Descriptor	LCK KINASE, SULFATE ION, 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, ... (4 entities in total)
Functional Keywords	alpha beta fold, transferase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P06239
Total number of polymer chains	1
Total formula weight	32944.79
Authors	Zhu, X.,Morgenstern, K.A. (deposition date: 1999-05-24, release date: 2000-05-31, Last modification date: 2011-07-13)
Primary citation	Zhu, X.,Kim, J.L.,Newcomb, J.R.,Rose, P.E.,Stover, D.R.,Toledo, L.M.,Zhao, H.,Morgenstern, K.A. Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors. Structure Fold.Des., 7:651-661, 1999 Cited by PubMed: 10404594 DOI: 10.1016/S0969-2126(99)80086-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation