1QNU

Shiga-Like Toxin I B Subunit Complexed with the Bridged-Starfish Inhibitor

Summary for 1QNU

Entry DOI	10.2210/pdb1qnu/pdb
Descriptor	Shiga toxin 1 variant B subunit, beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, METHYL-CARBAMIC ACID ETHYL ESTER, ... (5 entities in total)
Functional Keywords	toxin, subnanomolar inhibitor, multivalent protein-carbohydrate recognition, ob-fold
Biological source	Escherichia coli O157:H7
Total number of polymer chains	5
Total formula weight	42046.56
Authors	Pannu, N.S.,Hayakawa, K.,Read, R.J. (deposition date: 1999-10-21, release date: 2000-04-11, Last modification date: 2023-12-13)
Primary citation	Kitov, P.I.,Sadowska, J.M.,Mulvey, G.,Armstrong, G.D.,Ling, H.,Pannu, N.S.,Read, R.J.,Bundle, D.R. Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands. Nature, 403:669-672, 2000 Cited by PubMed: 10688205 DOI: 10.1038/35001095 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation