1QHC
CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH 5'-PHOSPHO-2'-DEOXYURIDINE-3'-PYROPHOSPHATE ADENOSINE-3'-PHOSPHATE
Summary for 1QHC
| Entry DOI | 10.2210/pdb1qhc/pdb |
| Related | 1AFK 1AFL 1AFU |
| Descriptor | PROTEIN (RIBONUCLEASE A), ADENYLATE-3'-PHOSPHATE-[[2'-DEOXY-URIDINE-5'-PHOSPHATE]-3'-PHOSPHATE] (3 entities in total) |
| Functional Keywords | hydrolase, ribonuclease, endonuclease, nucleotide inhibitor |
| Biological source | Bos taurus (cattle) |
| Cellular location | Secreted: P61823 |
| Total number of polymer chains | 2 |
| Total formula weight | 29011.35 |
| Authors | Leonidas, D.D.,Acharya, K.R. (deposition date: 1999-05-12, release date: 1999-08-31, Last modification date: 2023-08-16) |
| Primary citation | Leonidas, D.D.,Shapiro, R.,Irons, L.I.,Russo, N.,Acharya, K.R. Toward rational design of ribonuclease inhibitors: high-resolution crystal structure of a ribonuclease A complex with a potent 3',5'-pyrophosphate-linked dinucleotide inhibitor. Biochemistry, 38:10287-10297, 1999 Cited by PubMed: 10441122DOI: 10.1021/bi990900w PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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