1Q7L

Zn-binding domain of the T347G mutant of human aminoacylase-I

Summary for 1Q7L

• Entry DOI: 10.2210/pdb1q7l/pdb
• Descriptor: Aminoacylase-1, ZINC ION, GLYCINE, ... (5 entities in total)
• Functional Keywords: aminoacylase-1, catalysis, enzyme dimerization, site-directed mutagenesis, structure comparison, zinc, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q03154 Q03154
• Total number of polymer chains: 4
• Total formula weight: 65109.28

Authors

Lindner, H.A.,Lunin, V.V.,Alary, A.,Hecker, R.,Cygler, M.,Menard, R. (deposition date: 2003-08-19, release date: 2004-01-20, Last modification date: 2024-02-14)

• Primary citation: Lindner, H.A.,Lunin, V.V.,Alary, A.,Hecker, R.,Cygler, M.,Menard, R.; Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family.; J.Biol.Chem., 278:44496-44504, 2003; PubMed: 12933810; DOI: 10.1074/jbc.M304233200

Experimental method

X-RAY DIFFRACTION (1.4 Å)