1PYW

Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)

Summary for 1PYW

Entry DOI	10.2210/pdb1pyw/pdb
Related	1DLH 1KLU
Descriptor	HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DR-1 beta chain, 9-residue influenza virus hemagglutinin related peptide FVKQNA(MAA)AL, ... (5 entities in total)
Functional Keywords	mhc class ii, major histocompatibility protein complex, hla-dr1, influenza, hemagglutinin, superantigen, antigen, immune system-protein binding-toxin complex, immune system/protein binding/toxin
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane; Single-pass type I membrane protein: P01903
Total number of polymer chains	4
Total formula weight	71959.82
Authors	Zavala-Ruiz, Z.,Sundberg, E.J.,Stone, J.D.,DeOliveira, D.B.,Chan, I.C.,Svendsen, J.,Mariuzza, R.A.,Stern, L.J. (deposition date: 2003-07-09, release date: 2003-12-09, Last modification date: 2023-08-16)
Primary citation	Zavala-Ruiz, Z.,Sundberg, E.J.,Stone, J.D.,DeOliveira, D.B.,Chan, I.C.,Svendsen, J.,Mariuzza, R.A.,Stern, L.J. Exploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1 J.Biol.Chem., 278:44904-44912, 2003 Cited by PubMed: 12952957 DOI: 10.1074/jbc.M307652200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation