1PYO

Crystal Structure of Human Caspase-2 in Complex with Acetyl-Leu-Asp-Glu-Ser-Asp-cho

Summary for 1PYO

• Entry DOI: 10.2210/pdb1pyo/pdb
• Related PRD ID: PRD_000241
• Descriptor: Caspase-2, ACETYL-LEU-ASP-GLU-SER-ASJ, ... (4 entities in total)
• Functional Keywords: apoptosis, caspase, alpha-beta, thiol protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Mitochondrion outer membrane; Multi-pass membrane protein (By similarity): P36114
• Total number of polymer chains: 6
• Total formula weight: 62601.63

Authors

Schweizer, A.,Briand, C.,Grutter, M.G. (deposition date: 2003-07-09, release date: 2003-08-26, Last modification date: 2023-11-15)

• Primary citation: Schweizer, A.,Briand, C.,Grutter, M.G.; Crystal structure of caspase-2, apical initiator of the intrinsic apoptotic pathway.; J.Biol.Chem., 278:42441-42447, 2003; PubMed: 12920126; DOI: 10.1074/jbc.M304895200

Experimental method

X-RAY DIFFRACTION (1.65 Å)