1PTU

CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2)

1PTU の概要

• エントリーDOI: 10.2210/pdb1ptu/pdb
• 分子名称: PROTEIN TYROSINE PHOSPHATASE 1B, PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (3 entities in total)
• 機能のキーワード: hydrolase, acetylation, phosphorylation, complex (hydrolase-peptide) complex, complex (hydrolase/peptide)
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P18031
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38166.30

構造登録者

Barford, D.,Jia, Z. (登録日: 1995-04-21, 公開日: 1996-08-01, 最終更新日: 2021-11-03)

• 主引用文献: Jia, Z.,Barford, D.,Flint, A.J.,Tonks, N.K.; Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B.; Science, 268:1754-1758, 1995; PubMed: 7540771

実験手法

X-RAY DIFFRACTION (2.6 Å)