1PLG

EVIDENCE FOR THE EXTENDED HELICAL NATURE OF POLYSACCHARIDE EPITOPES. THE 2.8 ANGSTROMS RESOLUTION STRUCTURE AND THERMODYNAMICS OF LIGAND BINDING OF AN ANTIGEN BINDING FRAGMENT SPECIFIC FOR ALPHA-(2->8)-POLYSIALIC ACID

1PLG の概要

• エントリーDOI: 10.2210/pdb1plg/pdb
• 分子名称: IGG2A=KAPPA= (3 entities in total)
• 機能のキーワード: immunoglobulin
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Cell membrane; Single-pass membrane protein (Potential): P01865
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46760.03

構造登録者

Evans, S.V.,Sigurskjold, B.W.,Jennings, H.J.,Brisson, J.-R.,Tse, W.C.,To, R.,Altman, E.,Frosch, M.,Weisgerber, C.,Kratzin, H.,Klebert, S.,Vaesen, M.,Bitter-Suermann, D.,Rose, D.R.,Young, N.M.,Bundle, D.R. (登録日: 1995-04-24, 公開日: 1996-04-03, 最終更新日: 2012-02-22)

• 主引用文献: Evans, S.V.,Sigurskjold, B.W.,Jennings, H.J.,Brisson, J.R.,To, R.,Tse, W.C.,Altman, E.,Frosch, M.,Weisgerber, C.,Kratzin, H.D.,Klebert, S.,Vaesen, M.,Bitter-Suermann, D.,Rose, D.R.,Young, N.M.,Bundle, D.R.; Evidence for the extended helical nature of polysaccharide epitopes. The 2.8 A resolution structure and thermodynamics of ligand binding of an antigen binding fragment specific for alpha-(2-->8)-polysialic acid.; Biochemistry, 34:6737-6744, 1995; PubMed: 7538787; DOI: 10.1021/bi00020a019

実験手法

X-RAY DIFFRACTION (2.8 Å)