1PIV

BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14

1PIV の概要

• エントリーDOI: 10.2210/pdb1piv/pdb
• 分子名称: POLIOVIRUS TYPE 3 (SUBUNIT VP1), POLIOVIRUS TYPE 3 (SUBUNIT VP2), POLIOVIRUS TYPE 3 (SUBUNIT VP3), ... (7 entities in total)
• 機能のキーワード: virus, icosahedral virus
• 由来する生物種: Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B); 詳細
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03302 P03302 P03302 P03302
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 98449.06

構造登録者

Hiremath, C.N.,Grant, R.A.,Filman, D.J.,Hogle, J.M. (登録日: 1995-02-02, 公開日: 1995-06-03, 最終更新日: 2011-07-13)

• 主引用文献: Hiremath, C.N.,Grant, R.A.,Filman, D.J.,Hogle, J.M.; Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.; Acta Crystallogr.,Sect.D, 51:473-489, 1995; PubMed: 15299834; DOI: 10.1107/S090744499401084X

実験手法

X-RAY DIFFRACTION (2.9 Å)