1PIV

BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14

Summary for 1PIV

• Entry DOI: 10.2210/pdb1piv/pdb
• Descriptor: POLIOVIRUS TYPE 3 (SUBUNIT VP1), POLIOVIRUS TYPE 3 (SUBUNIT VP2), POLIOVIRUS TYPE 3 (SUBUNIT VP3), ... (7 entities in total)
• Functional Keywords: virus, icosahedral virus
• Biological source: Poliovirus type 3 (strains P3/LEON/37 AND P3/LEON 12A[1]B); More
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03302 P03302 P03302 P03302
• Total number of polymer chains: 5
• Total formula weight: 98449.06

Authors

Hiremath, C.N.,Grant, R.A.,Filman, D.J.,Hogle, J.M. (deposition date: 1995-02-02, release date: 1995-06-03, Last modification date: 2011-07-13)

• Primary citation: Hiremath, C.N.,Grant, R.A.,Filman, D.J.,Hogle, J.M.; Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.; Acta Crystallogr.,Sect.D, 51:473-489, 1995; PubMed: 15299834; DOI: 10.1107/S090744499401084X

Experimental method

X-RAY DIFFRACTION (2.9 Å)