1PFG

Strategy to design inhibitors: Structure of a complex of Proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5A resolution

Summary for 1PFG

Entry DOI	10.2210/pdb1pfg/pdb
Descriptor	Proteinase K, N-Ac-PAPFAAAA-NH2 (3 entities in total)
Functional Keywords	proteinase k, octapeptide, inhibitor, complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Engyodontium album More
Total number of polymer chains	2
Total formula weight	29697.69
Authors	Saxena, A.K.,Singh, T.P.,Peters, K.,Fittkau, S.,Betzel, C. (deposition date: 2003-05-27, release date: 2003-06-10, Last modification date: 2023-10-25)
Primary citation	Saxena, A.K.,Singh, T.P.,Peters, K.,Fittkau, S.,Betzel, C. Strategy to design peptide inhibitors: structure of a complex of proteinase K with a designed octapeptide inhibitor N-Ac-Pro-Ala-Pro-Phe-DAla-Ala-Ala-Ala-NH2 at 2.5 A resolution. Protein Sci., 5:2453-2458, 1996 Cited by PubMed: 8976553 DOI: 10.1002/pro.5560051207 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation