1PE4

SOLUTION STRUCTURE OF TOXIN CN12 FROM CENTRUROIDES NOXIUS ALFA SCORPION TOXIN ACTING ON SODIUM CHANNELS. NMR STRUCTURE

Summary for 1PE4

• Entry DOI: 10.2210/pdb1pe4/pdb
• Related: 1CN2
• NMR Information: BMRB: 5913
• Descriptor: Neurotoxin Cn11 (1 entity in total)
• Functional Keywords: toxin, scorpion toxin, centruroides noxius, sodium channels alpha toxin
• Biological source: Centruroides noxius (Mexican scorpion)
• Cellular location: Secreted: P63019
• Total number of polymer chains: 1
• Total formula weight: 7154.86

Authors

Del Rio-Portilla, F.,Hernandez-Marin, E.,Pimienta, G.,Coronas, F.V.,Zamudio, F.Z.,Rodrguez de la Vega, R.C.,Wanke, E.,Possani, L.D. (deposition date: 2003-05-21, release date: 2004-05-25, Last modification date: 2022-02-23)

• Primary citation: Del Rio-Portilla, F.,Hernandez-Marin, E.,Pimienta, G.,Coronas, F.V.,Zamudio, F.Z.,Rodrguez de la Vega, R.C.,Wanke, E.,Possani, L.D.; NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.; Eur.J.Biochem., 271:2504-2516, 2004; PubMed: 15182366; DOI: 10.1111/j.1432-1033.2004.04181.x

Experimental method

SOLUTION NMR