1P1V
Crystal Structure of FALS-associated human Copper-Zinc Superoxide Dismutase (CuZnSOD) Mutant D125H to 1.4A
Summary for 1P1V
Entry DOI | 10.2210/pdb1p1v/pdb |
Related | 1AZV 1OEZ 1OZT 1OZU |
Descriptor | Superoxide dismutase [Cu-Zn], SULFATE ION, ZINC ION, ... (4 entities in total) |
Functional Keywords | beta-barrel, bound anion at copper site, cuznsod peroxidation mechanism, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00441 |
Total number of polymer chains | 3 |
Total formula weight | 48280.51 |
Authors | Elam, J.S.,Malek, K.,Rodriguez, J.A.,Doucette, P.A.,Taylor, A.B.,Hayward, L.J.,Cabelli, D.E.,Valentine, J.S.,Hart, P.J. (deposition date: 2003-04-14, release date: 2003-08-26, Last modification date: 2021-10-27) |
Primary citation | Elam, J.S.,Malek, K.,Rodriguez, J.A.,Doucette, P.A.,Taylor, A.B.,Hayward, L.J.,Cabelli, D.E.,Valentine, J.S.,Hart, P.J. An Alternative Mechanism of Bicarbonate-mediated Peroxidation by Copper-Zinc Superoxide Dismutase: RATES ENHANCED VIA PROPOSED ENZYME-ASSOCIATED PEROXYCARBONATE INTERMEDIATE J.Biol.Chem., 278:21032-21039, 2003 Cited by PubMed: 12649272DOI: 10.1074/jbc.M300484200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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