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1OZ1

P38 MITOGEN-ACTIVATED KINASE IN COMPLEX WITH 4-AZAINDOLE INHIBITOR

Summary for 1OZ1
Entry DOI10.2210/pdb1oz1/pdb
DescriptorMitogen-activated protein kinase 14, 3-(4-FLUOROPHENYL)-2-PYRIDIN-4-YL-1H-PYRROLO[3,2-B]PYRIDIN-1-OL (3 entities in total)
Functional Keywordsser/thr protein kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity): Q16539
Total number of polymer chains1
Total formula weight43054.02
Authors
Lovejoy, B.,Villasenor, A.,Browner, M.,Dunten, P. (deposition date: 2003-04-07, release date: 2003-09-23, Last modification date: 2024-02-14)
Primary citationTrejo, A.,Arzeno, H.,Browner, M.,Chanda, S.,Cheng, S.,Comer, D.D.,Dalrymple, S.A.,Dunten, P.,Lafargue, J.,Lovejoy, B.,Freire-Moar, J.,Lim, J.,Mcintosh, J.,Miller, J.,Papp, E.,Reuter, D.,Roberts, R.,Sanpablo, F.,Saunders, J.,Song, K.,Villasenor, A.,Warren, S.D.,Welch, M.,Weller, P.,Whiteley, P.E.,Zeng, L.,Goldstein, D.M.
Design and synthesis of 4-azaindoles as inhibitors of p38 MAP kinase.
J.Med.Chem., 46:4702-4713, 2003
Cited by
PubMed: 14561090
DOI: 10.1021/jm0301787
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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