1OW0

Crystal structure of human FcaRI bound to IgA1-Fc

Summary for 1OW0

• Entry DOI: 10.2210/pdb1ow0/pdb
• Related: 1OVZ
• Descriptor: Ig alpha-1 chain C region, Immunoglobulin alpha Fc receptor, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: iga1, fcari, cd89, antibody, fc receptor, immunoglobulin-like domain, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Isoform A. Isoform A. Isoform A. Isoform B: Secreted. Isoform B-delta-S2: Secreted: P24071
• Total number of polymer chains: 4
• Total formula weight: 102370.16

Authors

Herr, A.B.,Ballister, E.R.,Bjorkman, P.J. (deposition date: 2003-03-27, release date: 2003-05-27, Last modification date: 2023-08-16)

• Primary citation: Herr, A.B.,Ballister, E.R.,Bjorkman, P.J.; Insights into IgA-mediated immune responses from the crystal structures of human Fc-alpha-RI and its complex with IgA1-Fc; Nature, 423:614-620, 2003; PubMed: 12768205; DOI: 10.1038/nature01685

Experimental method

X-RAY DIFFRACTION (3.1 Å)