1OSN

Crystal structure of Varicella zoster virus thymidine kinase in complex with BVDU-MP and ADP

Summary for 1OSN

Entry DOI	10.2210/pdb1osn/pdb
Descriptor	Thymidine kinase, ADENOSINE-5'-DIPHOSPHATE, (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywords	human herpes virus 3, chickenpox, thymidine kinase, bvdu-mp, transferase
Biological source	Human herpesvirus 3 (Varicella-zoster virus)
Total number of polymer chains	4
Total formula weight	154884.64
Authors	Bird, L.E.,Ren, J.,Wright, A.,Leslie, K.D.,Degreve, B.,Balzarini, J.,Stammers, D.K. (deposition date: 2003-03-20, release date: 2003-06-10, Last modification date: 2023-10-25)
Primary citation	Bird, L.E.,Ren, J.,Wright, A.,Leslie, K.D.,Degreve, B.,Balzarini, J.,Stammers, D.K. Crystal structure of varicella zoster virus thymidine kinase J.Biol.Chem., 278:24680-24687, 2003 Cited by PubMed: 12686543 DOI: 10.1074/jbc.M302025200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation