1OSE

Porcine pancreatic alpha-amylase complexed with acarbose

Summary for 1OSE

Entry DOI	10.2210/pdb1ose/pdb
Descriptor	PORCINE ALPHA-AMYLASE, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	alpha-amylase, acarbose, hydrolase (o-glycosyl), hydrolase
Biological source	Sus scrofa (pig)
Total number of polymer chains	1
Total formula weight	56620.31
Authors	Gilles, C.,Payan, F. (deposition date: 1996-03-20, release date: 1997-04-01, Last modification date: 2020-07-29)
Primary citation	Gilles, C.,Astier, J.P.,Marchis-Mouren, G.,Cambillau, C.,Payan, F. Crystal structure of pig pancreatic alpha-amylase isoenzyme II, in complex with the carbohydrate inhibitor acarbose. Eur.J.Biochem., 238:561-569, 1996 Cited by PubMed: 8681972 DOI: 10.1111/j.1432-1033.1996.0561z.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation