1OMW

Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits

1OMW の概要

• エントリーDOI: 10.2210/pdb1omw/pdb
• 分子名称: G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, ... (4 entities in total)
• 機能のキーワード: wd-40 repeat, transferase
• 由来する生物種: Bos taurus (cattle); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P63212
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 125573.51

構造登録者

Lodowski, D.T.,Pitcher, J.A.,Capel, W.D.,Lefkowitz, R.J.,Tesmer, J.J.G. (登録日: 2003-02-26, 公開日: 2003-06-03, 最終更新日: 2023-08-16)

• 主引用文献: Lodowski, D.T.,Pitcher, J.A.,Capel, W.D.,Lefkowitz, R.J.,Tesmer, J.J.G.; Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma; Science, 300:1256-1262, 2003; PubMed: 12764189; DOI: 10.1126/science.1082348

実験手法

X-RAY DIFFRACTION (2.5 Å)