1O8T

Global Structure and Dynamics of Human Apolipoprotein CII in Complex with Micelles: Evidence for increased mobility of the helix involved in the activation of lipoprotein lipase

Summary for 1O8T

Entry DOI	10.2210/pdb1o8t/pdb
Related	1BY6 1I5J
Descriptor	APOLIPOPROTEIN C-II (1 entity in total)
Functional Keywords	apocii, lpl, activation mechanism, domain motion, sds, micelle, global structure, local structure, dynamics, helix, lipid transport, lipid degradation, chylomicron
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Secreted: P02655
Total number of polymer chains	1
Total formula weight	8921.86
Authors	Zdunek, J.,Martinez, G.V.,Schleucher, J.,Lycksell, P.O.,Yin, Y.,Nilsson, S.,Shen, Y.,Olivecrona, G.,Wijmenga, S. (deposition date: 2002-11-29, release date: 2003-02-27, Last modification date: 2011-07-13)
Primary citation	Zdunek, J.,Martinez, G.V.,Schleucher, J.,Lycksell, P.O.,Yin, Y.,Nilsson, S.,Shen, Y.,Olivecrona, G.,Wijmenga, S. Global Structure and Dynamics of Human Apolipoprotein Cii in Complex with Micelles: Evidence for Increased Mobility of the Helix Involved in the Activation of Lipoprotein Lipase Biochemistry, 42:1872-, 2003 Cited by PubMed: 12590574 DOI: 10.1021/BI0267184 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation