1O7A

Human beta-Hexosaminidase B

Summary for 1O7A

• Entry DOI: 10.2210/pdb1o7a/pdb
• Related: 1QBD
• Descriptor: BETA-HEXOSAMINIDASE BETA CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-(acetylamido)-2-deoxy-D-glucono-1,5-lactone, ... (6 entities in total)
• Functional Keywords: hydrolase, glycosyl hydrolase, hexosaminidase, lysosomal, sphingolipid degradation, sandhoff disease, ba8-barrel, glycosidase
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 6
• Total formula weight: 359674.09

Authors

Maier, T.,Strater, N.,Schuette, C.,Klingenstein, R.,Sandhoff, K.,Saenger, W. (deposition date: 2002-10-29, release date: 2003-10-23, Last modification date: 2020-11-18)

• Primary citation: Maier, T.,Strater, N.,Schuette, C.,Klingenstein, R.,Sandhoff, K.,Saenger, W.; The X-Ray Crystal Structure of Human Beta-Hexosaminidase B Provides New Insights Into Sandhoff Disease; J.Mol.Biol., 328:669-, 2003; PubMed: 12706724; DOI: 10.1016/S0022-2836(03)00311-5

Experimental method

X-RAY DIFFRACTION (2.25 Å)