1NW9

STRUCTURE OF CASPASE-9 IN AN INHIBITORY COMPLEX WITH XIAP-BIR3

1NW9 の概要

• エントリーDOI: 10.2210/pdb1nw9/pdb
• 分子名称: Baculoviral IAP repeat-containing protein 4, caspase 9, apoptosis-related cysteine protease, ZINC ION (3 entities in total)
• 機能のキーワード: caspase-9, xiap, caspase inhibition, caspase activation, dimerization, apoptosis
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 41866.65

構造登録者

Shiozaki, E.N.,Chai, J.,Rigotti, D.J.,Riedl, S.J.,Li, P.,Srinivasula, S.M.,Alnemri, E.S.,Fairman, R.,Shi, Y. (登録日: 2003-02-05, 公開日: 2003-03-25, 最終更新日: 2024-02-14)

• 主引用文献: Shiozaki, E.N.,Chai, J.,Rigotti, D.J.,Riedl, S.J.,Li, P.,Srinivasula, S.M.,Alnemri, E.S.,Fairman, R.,Shi, Y.; Mechanism of XIAP-Mediated Inhibition of Caspase-9; Mol.Cell, 11:519-527, 2003; PubMed: 12620238; DOI: 10.1016/S1097-2765(03)00054-6

実験手法

X-RAY DIFFRACTION (2.4 Å)