1NVS

The Complex Structure Of Checkpoint Kinase Chk1/SB218078

Summary for 1NVS

• Entry DOI: 10.2210/pdb1nvs/pdb
• Related: 1nvq
• Descriptor: Serine/threonine-protein kinase Chk1, Peptide ASVSA, SULFATE ION, ... (5 entities in total)
• Functional Keywords: chk1-sb218078 complex, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O14757
• Total number of polymer chains: 2
• Total formula weight: 33965.90

Authors

Zhao, B.,Bower, M.J.,McDevitt, P.J.,Zhao, H.,Davis, S.T.,Johanson, K.O.,Green, S.M.,Concha, N.O.,Zhou, B.B. (deposition date: 2003-02-04, release date: 2003-04-08, Last modification date: 2023-08-16)

• Primary citation: Zhao, B.,Bower, M.J.,McDevitt, P.J.,Zhao, H.,Davis, S.T.,Johanson, K.O.,Green, S.M.,Concha, N.O.,Zhou, B.B.; Structural Basis for Chk1 Inhibition by UCN-01; J.Biol.Chem., 277:46609-46615, 2002; PubMed: 12244092; DOI: 10.1074/jbc.M201233200

Experimental method

X-RAY DIFFRACTION (1.8 Å)