1NQI

crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc

Replaces:  1J92

Summary for 1NQI

• Entry DOI: 10.2210/pdb1nqi/pdb
• Descriptor: ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: lactose synthase, n-acetylglucosamine binding, transferase activator-transferase complex, transferase activator/transferase
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 94257.48

Authors

Ramakrishnan, B.,Qasba, P.K. (deposition date: 2003-01-21, release date: 2003-02-04, Last modification date: 2020-07-29)

• Primary citation: Ramakrishnan, B.,Qasba, P.K.; Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta-1,4-galactosyltransferase; J.Mol.Biol., 310:205-218, 2001; PubMed: 11419947; DOI: 10.1006/jmbi.2001.4757

Experimental method

X-RAY DIFFRACTION (2 Å)