1NIZ

NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody

Summary for 1NIZ

• Entry DOI: 10.2210/pdb1niz/pdb
• Related: 1NJ0
• Descriptor: Exterior membrane glycoprotein(GP120) (1 entity in total)
• Functional Keywords: peptide-antibody complex, b-hairpin, viral protein
• Biological source: Human immunodeficiency virus 1
• Cellular location: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P05877
• Total number of polymer chains: 1
• Total formula weight: 1907.27

Authors

Sharon, M.,Kessler, N.,Levy, R.,Zolla-Pazner, S.,Gorlach, M.,Anglister, J. (deposition date: 2002-12-30, release date: 2003-02-25, Last modification date: 2022-02-23)

• Primary citation: Sharon, M.,Kessler, N.,Levy, R.,Zolla-Pazner, S.,Gorlach, M.,Anglister, J.; Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.; Structure, 11:225-236, 2003; PubMed: 12575942; DOI: 10.1016/S0969-2126(03)00011-X

Experimental method

SOLUTION NMR