1NFY

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR200095

Summary for 1NFY

• Entry DOI: 10.2210/pdb1nfy/pdb
• Related: 1EZQ 1F0R 1F0S 1NFU 1NFW 1NFX
• Descriptor: Coagulation factor XA, heavy chain, Coagulation factor XA, light chain, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 2
• Total formula weight: 44264.44

Authors

Maignan, S.,Guilloteau, J.P. (deposition date: 2002-12-16, release date: 2003-02-25, Last modification date: 2011-07-13)

• Primary citation: Maignan, S.,Guilloteau, J.P.,Choi-Sledeski, Y.M.,Becker, M.R.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V.; Molecular structures of human Factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket.; J.Med.Chem., 46:685-690, 2003; PubMed: 12593649; DOI: 10.1021/jm0203837

Experimental method

X-RAY DIFFRACTION (2.1 Å)