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1NFU

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR132747

Summary for 1NFU
Entry DOI10.2210/pdb1nfu/pdb
Related1EZQ 1F0R 1F0S 1NFW 1NFX 1NFY
DescriptorCOAGULATION FACTOR XA, HEAVY CHAIN, COAGULATION FACTOR XA, LIGHT CHAIN, CALCIUM ION, ... (5 entities in total)
Functional Keywordshydrolase
Biological sourceHomo sapiens (human)
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Cellular locationSecreted: P00742 P00742
Total number of polymer chains2
Total formula weight50973.61
Authors
Maignan, S.,Guilloteau, J.P. (deposition date: 2002-12-16, release date: 2003-02-25, Last modification date: 2023-08-16)
Primary citationMaignan, S.,Guilloteau, J.P.,Choi-Sledeski, Y.M.,Becker, M.R.,Ewing, W.R.,Pauls, H.W.,Spada, A.P.,Mikol, V.
Molecular structures of human Factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket.
J.Med.Chem., 46:685-690, 2003
Cited by
PubMed: 12593649
DOI: 10.1021/jm0203837
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.05 Å)
Structure validation

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