1NC4

Crystal Structure of Monoclonal Antibody 2D12.5 Fab Complexed with Gd-DOTA

Summary for 1NC4

Entry DOI	10.2210/pdb1nc4/pdb
Related	1NC2
Descriptor	MONOCLONAL ANTIBODY 2D12.5, LAMBDA LIGHT CHAIN, MONOCLONAL ANTIBODY 2D12.5, IGG1 GAMMA HEAVY CHAIN, CHLORIDE ION, ... (8 entities in total)
Functional Keywords	antibody-dota complex, rare earth, dota, metal chelate, gadolinium, gamma turn, n-linked glycosylation, immune system
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	4
Total formula weight	95529.09
Authors	Corneillie, T.M.,Fisher, A.J.,Meares, C.F. (deposition date: 2002-12-04, release date: 2003-12-16, Last modification date: 2023-08-16)
Primary citation	Corneillie, T.M.,Fisher, A.J.,Meares, C.F. Crystal structures of two complexes of the rare-earth-DOTA-binding antibody 2D12.5: ligand generality from a chiral system. J.Am.Chem.Soc., 125:15039-15048, 2003 Cited by PubMed: 14653738 DOI: 10.1021/ja037236y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation