1NB8

Structure of the catalytic domain of USP7 (HAUSP)

Summary for 1NB8

• Entry DOI: 10.2210/pdb1nb8/pdb
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 7 (2 entities in total)
• Functional Keywords: ubp, deubiquitination, hausp, p53 binding, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q93009
• Total number of polymer chains: 2
• Total formula weight: 82852.79

Authors

Hu, M.,Li, P.,Li, M.,Li, W.,Yao, T.,Wu, J.-W.,Gu, W.,Cohen, R.E.,Shi, Y. (deposition date: 2002-12-02, release date: 2003-01-07, Last modification date: 2018-04-04)

• Primary citation: Hu, M.,Li, P.,Li, M.,Li, W.,Yao, T.,Wu, J.-W.,Gu, W.,Cohen, R.E.,Shi, Y.; Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde; Cell(Cambridge,Mass.), 111:1041-1054, 2002; PubMed: 12507430; DOI: 10.1016/S0092-8674(02)01199-6

Experimental method

X-RAY DIFFRACTION (2.3 Å)