1N6B

Microsomal Cytochrome P450 2C5/3LVdH Complex with a dimethyl derivative of sulfaphenazole

1N6B の概要

• エントリーDOI: 10.2210/pdb1n6b/pdb
• 関連するPDBエントリー: 1DT6
• 分子名称: Cytochrome P450 2C5, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
• 機能のキーワード: membrane protein, progesterone 21-hydroxylase, benzo(a), pyrene hydroxylase, estradiol 2-hydroxylase, p450, cyp2c5, dimethylsulfaphenazole complex, oxidoreductase
• 由来する生物種: Oryctolagus cuniculus (rabbit)
• 細胞内の位置: Endoplasmic reticulum membrane (By similarity): P00179
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 55020.26

構造登録者

Wester, M.R.,Johnson, E.F.,Marques-Soares, C.,Dansette, P.M.,Mansuy, D.,Stout, C.D. (登録日: 2002-11-09, 公開日: 2003-06-03, 最終更新日: 2024-02-14)

• 主引用文献: Wester, M.R.,Johnson, E.F.,Marques-Soares, C.,Dansette, P.M.,Mansuy, D.,Stout, C.D.; Structure of a Substrate Complex of Mammalian Cytochrome P450 2C5 at 2.3 A Resolution: Evidence for Multiple Substrate Binding Modes; Biochemistry, 42:6370-6379, 2003; PubMed: 12767218; DOI: 10.1021/bi0273922

実験手法

X-RAY DIFFRACTION (2.3 Å)