1N6B

Microsomal Cytochrome P450 2C5/3LVdH Complex with a dimethyl derivative of sulfaphenazole

Summary for 1N6B

Entry DOI	10.2210/pdb1n6b/pdb
Related	1DT6
Descriptor	Cytochrome P450 2C5, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywords	membrane protein, progesterone 21-hydroxylase, benzo(a), pyrene hydroxylase, estradiol 2-hydroxylase, p450, cyp2c5, dimethylsulfaphenazole complex, oxidoreductase
Biological source	Oryctolagus cuniculus (rabbit)
Cellular location	Endoplasmic reticulum membrane (By similarity): P00179
Total number of polymer chains	1
Total formula weight	55020.26
Authors	Wester, M.R.,Johnson, E.F.,Marques-Soares, C.,Dansette, P.M.,Mansuy, D.,Stout, C.D. (deposition date: 2002-11-09, release date: 2003-06-03, Last modification date: 2024-02-14)
Primary citation	Wester, M.R.,Johnson, E.F.,Marques-Soares, C.,Dansette, P.M.,Mansuy, D.,Stout, C.D. Structure of a Substrate Complex of Mammalian Cytochrome P450 2C5 at 2.3 A Resolution: Evidence for Multiple Substrate Binding Modes Biochemistry, 42:6370-6379, 2003 Cited by PubMed: 12767218 DOI: 10.1021/bi0273922 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation