1N2V

Crystal Structure of TGT in complex with 2-Butyl-5,6-dihydro-1H-imidazo[4,5-d]pyridazine-4,7-dione

Summary for 1N2V

Entry DOI	10.2210/pdb1n2v/pdb
Related	1ENU 1PUD
Descriptor	Queuine tRNA-ribosyltransferase, ZINC ION, 2-BUTYL-5,6-DIHYDRO-1H-IMIDAZO[4,5-D]PYRIDAZINE-4,7-DIONE, ... (4 entities in total)
Functional Keywords	protein-ligand complex, transferase
Biological source	Zymomonas mobilis
Total number of polymer chains	1
Total formula weight	43199.33
Authors	Brenk, R.,Naerum, L.,Graedler, U.,Gerber, H.-D.,Garcia, G.A.,Reuter, K.,Stubbs, M.T.,Klebe, G. (deposition date: 2002-10-24, release date: 2003-04-08, Last modification date: 2024-02-14)
Primary citation	Brenk, R.,Naerum, L.,Graedler, U.,Gerber, H.-D.,Garcia, G.A.,Reuter, K.,Stubbs, M.T.,Klebe, G. Virtual screening for submicromolar leads of tRNA-guanine transglycosylase based on a new unexpected binding mode detected by crystal structure analysis J.Med.Chem., 46:1133-1143, 2003 Cited by PubMed: 12646024 DOI: 10.1021/jm0209937 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation