1MPL

CRYSTAL STRUCTURE OF PHOSPHONATE-INHIBITED D-ALA-D-ALA PEPTIDASE REVEALS AN ANALOG OF A TETRAHEDRAL TRANSITION STATE

Summary for 1MPL

Entry DOI	10.2210/pdb1mpl/pdb
Related	1IKG 1IKI
Descriptor	D-alanyl-D-alanine carboxypeptidase, GLYCYL-L-A-AMINOPIMELYL-E-(D-2-AMINOETHYL)PHOSPHONATE, GLYCEROL, ... (4 entities in total)
Functional Keywords	transition state analog, peptidoglycan, penicillin binding protein, hydrolase
Biological source	Streptomyces sp.
Total number of polymer chains	1
Total formula weight	38221.32
Authors	Silvaggi, N.R.,Anderson, J.W.,Brinsmade, S.R.,Pratt, R.F.,Kelly, J.A. (deposition date: 2002-09-12, release date: 2003-02-25, Last modification date: 2019-07-24)
Primary citation	Silvaggi, N.R.,Anderson, J.W.,Brinsmade, S.R.,Pratt, R.F.,Kelly, J.A. The Crystal Structure of Phosphonate-Inhibited d-Ala-d-Ala Peptidase Reveals an Analogue of a Tetrahedral Transition State. Biochemistry, 42:1199-1208, 2003 Cited by PubMed: 12564922 DOI: 10.1021/bi0268955 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.12 Å)

Structure validation