1MP8

Crystal structure of Focal Adhesion Kinase (FAK)

Summary for 1MP8

• Entry DOI: 10.2210/pdb1mp8/pdb
• Related: 1MQ4 1MQB
• Descriptor: focal adhesion kinase 1, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: tyrosine protein kinase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cell junction, focal adhesion: Q05397
• Total number of polymer chains: 1
• Total formula weight: 32547.34

Authors

Nowakowski, J.,Cronin, C.N.,McRee, D.E.,Knuth, M.W.,Nelson, C.G.,Pavletich, N.P.,Rodgers, J.,Sang, B.-C.,Scheibe, D.N.,Swanson, R.V.,Thompson, D.A. (deposition date: 2002-09-11, release date: 2003-09-16, Last modification date: 2011-07-13)

• Primary citation: Nowakowski, J.,Cronin, C.N.,McRee, D.E.,Knuth, M.W.,Nelson, C.G.,Pavletich, N.P.,Rodgers, J.,Sang, B.-C.,Scheibe, D.N.,Swanson, R.V.,Thompson, D.A.; Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography; Structure, 10:1659-1667, 2002; PubMed: 12467573; DOI: 10.1016/S0969-2126(02)00907-3

Experimental method

X-RAY DIFFRACTION (1.6 Å)