1MJV
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C51A and C60A)
Summary for 1MJV
| Entry DOI | 10.2210/pdb1mjv/pdb |
| Related | 1MKG 1MKK 2VPF |
| Descriptor | Vascular Endothelial Growth Factor A (2 entities in total) |
| Functional Keywords | cystine-knot growth factor, hormone-growth factor complex, hormone/growth factor |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted : P15692 |
| Total number of polymer chains | 2 |
| Total formula weight | 22391.93 |
| Authors | Muller, Y.A.,Heiring, C.,Misselwitz, R.,Welfle, K.,Welfle, H. (deposition date: 2002-08-28, release date: 2002-12-11, Last modification date: 2021-10-27) |
| Primary citation | Muller, Y.A.,Heiring, C.,Misselwitz, R.,Welfle, K.,Welfle, H. The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor J.Biol.Chem., 277:43410-43416, 2002 Cited by PubMed: 12207021DOI: 10.1074/jbc.M206438200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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