1MJ7

Crystal Structure Of The Complex Of The Fab fragment of Esterolytic Antibody MS5-393 and A Transition-State Analog

Summary for 1MJ7

• Entry DOI: 10.2210/pdb1mj7/pdb
• Related: 1MH5 1MIE 1MJ8 1MJJ 1MJU
• Descriptor: IMMUNOGLOBULIN MS5-393, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE, ... (4 entities in total)
• Functional Keywords: catalytic antibody, ester hydrolysis, esterolytic, fab, immunoglobulin, tsa, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 49214.85

Authors

Ruzheinikov, S.N.,Muranova, T.A.,Sedelnikova, S.E.,Partridge, L.J.,Blackburn, G.M.,Murray, I.A.,Kakinuma, H.,Takashi, N.,Shimazaki, K.,Sun, J.,Nishi, Y.,Rice, D.W. (deposition date: 2002-08-27, release date: 2003-09-23, Last modification date: 2011-11-16)

• Primary citation: Ruzheinikov, S.N.,Muranova, T.A.,Sedelnikova, S.E.,Partridge, L.J.,Blackburn, G.M.,Murray, I.A.,Kakinuma, H.,Takashi, N.,Shimazaki, K.,Sun, J.,Nishi, Y.,Rice, D.W.; High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity; J.Mol.Biol., 332:423-435, 2003; PubMed: 12948492; DOI: 10.1016/S0022-2836(03)00902-1

Experimental method

X-RAY DIFFRACTION (2.25 Å)