1MH5

The Structure Of The Complex Of The Fab Fragment Of The Esterolytic Antibody MS6-164 and A Transition-State Analog

1MH5 の概要

• エントリーDOI: 10.2210/pdb1mh5/pdb
• 関連するPDBエントリー: 1MIE 1MJ7 1MJ8 1MJJ 1MJU
• 分子名称: IMMUNOGLOBULIN MS6-164, SULFATE ION, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE, ... (5 entities in total)
• 機能のキーワード: catalytic antibody, ester hydrolysis, esterolytic, fab, immunoglobulin, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 99216.72

構造登録者

Ruzheinikov, S.N.,Muranova, T.A.,Sedelnikova, S.E.,Partridge, L.J.,Blackburn, G.M.,Murray, I.A.,Kakinuma, H.,Takashi, N.,Shimazaki, K.,Sun, J.,Nishi, Y.,Rice, D.W. (登録日: 2002-08-19, 公開日: 2003-09-23, 最終更新日: 2011-11-16)

• 主引用文献: Ruzheinikov, S.N.,Muranova, T.A.,Sedelnikova, S.E.,Partridge, L.J.,Blackburn, G.M.,Murray, I.A.,Kakinuma, H.,Takashi, N.,Shimazaki, K.,Sun, J.,Nishi, Y.,Rice, D.W.; High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity; J.Mol.Biol., 332:423-435, 2003; PubMed: 12948492; DOI: 10.1016/S0022-2836(03)00902-1

実験手法

X-RAY DIFFRACTION (2.1 Å)