1MC0

Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains

Summary for 1MC0

Entry DOI	10.2210/pdb1mc0/pdb
Descriptor	3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE (3 entities in total)
Functional Keywords	gaf domain, 3', 5'-cyclic nucleotide phosphodiesterase, 5'-guanosine monophosphate, hydrolase
Biological source	Mus musculus (house mouse)
Cellular location	Membrane; Peripheral membrane protein (Potential): Q922S4
Total number of polymer chains	1
Total formula weight	41769.12
Authors	Martinez, S.,Wu, A.,Glavas, N.,Tang, X.,Turley, S.,Hol, W.,Beavo, J. (deposition date: 2002-08-04, release date: 2002-10-02, Last modification date: 2011-07-13)
Primary citation	Martinez, S.E.,Wu, A.Y.,Glavas, N.A.,Tang, X.B.,Turley, S.,Hol, W.G.,Beavo, J.A. The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding. Proc.Natl.Acad.Sci.USA, 99:13260-13265, 2002 Cited by PubMed: 12271124 DOI: 10.1073/pnas.192374899 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.86 Å)

Structure validation