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1MBM

NSP4 proteinase from Equine Arteritis Virus

Summary for 1MBM
Entry DOI10.2210/pdb1mbm/pdb
Related1CQQ 1HAV 1HPG 1L1N
Descriptorchymotrypsin-like serine protease (2 entities in total)
Functional Keywordsserine proteinase, chymotrypsin-like proteinase, collapsed oxyanion hole, transferase
Biological sourceEquine arteritis virus
Cellular locationNsp1 papain-like cysteine proteinase: Host nucleus. Nsp2 cysteine proteinase: Host membrane ; Multi-pass membrane protein . Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 5-6-7: Host membrane ; Multi-pass membrane protein . 3C-like serine proteinase: Host cytoplasm . RNA-directed RNA polymerase: Host cytoplasm, host perinuclear region . Helicase: Host cytoplasm, host perinuclear region : P19811
Total number of polymer chains4
Total formula weight81510.80
Authors
Barrette-Ng, I.H.,Ng, K.K.-S.,Mark, B.L.,van Aken, D.,Cherney, M.M.,Garen, C.,Kolodenko, Y.,Gorbalenya, A.E.,Snijder, E.J.,James, M.N.G. (deposition date: 2002-08-03, release date: 2002-10-23, Last modification date: 2024-02-14)
Primary citationBarrette-Ng, I.H.,Ng, K.K.-S.,Mark, B.L.,van Aken, D.,Cherney, M.M.,Garen, C.,Kolodenko, Y.,Gorbalenya, A.E.,Snijder, E.J.,James, M.N.G.
Structure of Arterivirus nsp4: the smallest chymotrypsin-like proteinase with an alpha/beta C-terminal extension and alternate conformations of the oxyanion hole
J.Biol.Chem., 277:39960-39966, 2002
Cited by
PubMed: 12163505
DOI: 10.1074/jbc.M206978200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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