1MA3
Structure of a Sir2 enzyme bound to an acetylated p53 peptide
Summary for 1MA3
| Entry DOI | 10.2210/pdb1ma3/pdb |
| Descriptor | Transcriptional regulatory protein, Sir2 family, Cellular tumor antigen p53, ZINC ION, ... (5 entities in total) |
| Functional Keywords | enzyme-substrate complex, protein binding, transcription |
| Biological source | Archaeoglobus fulgidus More |
| Cellular location | Cytoplasm (Probable): O30124 Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 |
| Total number of polymer chains | 2 |
| Total formula weight | 30937.17 |
| Authors | Avalos, J.L.,Celic, I.,Muhammad, S.,Cosgrove, M.S.,Boeke, J.D.,Wolberger, C. (deposition date: 2002-07-31, release date: 2002-10-16, Last modification date: 2011-07-13) |
| Primary citation | Avalos, J.L.,Celic, I.,Muhammad, S.,Cosgrove, M.S.,Boeke, J.D.,Wolberger, C. Structure of a Sir2 enzyme bound to an acetylated p53 peptide Mol.Cell, 10:523-535, 2002 Cited by PubMed: 12408821DOI: 10.1016/S1097-2765(02)00628-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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