1M7P

Plasmodium Falciparum Triosephosphate isomerase (PfTIM) compled to substrate analog glycerol-3-phosphate (G3P).

Summary for 1M7P

Entry DOI	10.2210/pdb1m7p/pdb
Related	1LYX 1LZO 1M7O 1YDV
Descriptor	Triosephosphate Isomerase, GLYCERALDEHYDE-3-PHOSPHATE (3 entities in total)
Functional Keywords	tim barrles; beta-alpha barrels; enzyme-inhibitor complex, isomerase
Biological source	Plasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains	2
Total formula weight	56335.59
Authors	Parthasarathy, S.,Balaram, H.,Balaram, P.,Murthy, M.R.N. (deposition date: 2002-07-22, release date: 2002-11-29, Last modification date: 2024-02-14)
Primary citation	Parthasarathy, S.,Balaram, H.,Balaram, P.,Murthy, M.R. Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state. Acta Crystallogr.,Sect.D, 58:1992-2000, 2002 Cited by PubMed: 12454456 DOI: 10.1107/S0907444902015433 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation