1M1U

AN ISOLEUCINE-BASED ALLOSTERIC SWITCH CONTROLS AFFINITY AND SHAPE SHIFTING IN INTEGRIN CD11B A-DOMAIN

Summary for 1M1U

Entry DOI	10.2210/pdb1m1u/pdb
Related	1IDO 1M1X
Descriptor	Integrin alpha-M, CALCIUM ION (3 entities in total)
Functional Keywords	integrin, cell adhesion protein, glycoprotein, a-domain, cd11b, cell adhesion
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type I membrane protein: P11215
Total number of polymer chains	1
Total formula weight	22301.39
Authors	Xiong, J.-P.,Li, R.,Essafi, M.,Stehle, T.,Arnaout, M.A. (deposition date: 2002-06-20, release date: 2002-08-07, Last modification date: 2024-02-14)
Primary citation	Xiong, J.P.,Li, R.,Essafi, M.,Stehle, T.,Arnaout, M.A. An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain. J.Biol.Chem., 275:38762-38767, 2000 Cited by PubMed: 11034990 DOI: 10.1074/jbc.C000563200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation