1M16

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V).

Summary for 1M16

• Entry DOI: 10.2210/pdb1m16/pdb
• Related: 1JQZ
• Descriptor: acidic fibroblast growth factor, SULFATE ION, FORMIC ACID, ... (4 entities in total)
• Functional Keywords: beta-trefoil, hormone-growth factor complex, hormone/growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P05230
• Total number of polymer chains: 2
• Total formula weight: 33717.68

Authors

Brych, S.R.,Kim, J.,Spielmann, G.L.,Logan, T.M.,Blaber, M. (deposition date: 2002-06-17, release date: 2003-08-05, Last modification date: 2024-02-14)

• Primary citation: Brych, S.R.,Kim, J.,Logan, T.M.,Blaber, M.; Accommodation of a highly symmetric core within a symmetric protein superfold; Protein Sci., 12:2704-2718, 2003; PubMed: 14627732; DOI: 10.1110/ps.03374903

Experimental method

X-RAY DIFFRACTION (1.7 Å)