1M05

HLA B8 in complex with an Epstein Barr Virus determinant

1M05 の概要

• エントリーDOI: 10.2210/pdb1m05/pdb
• 関連するPDBエントリー: 1AGE
• 分子名称: HLA class I histocompatibility antigen, B-8 B*0801 alpha chain, Beta-2-microglobulin, EBNA-3 nuclear protein, ... (5 entities in total)
• 機能のキーワード: mhc class i, hla b8, epstein barr virus, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P30460; Secreted . Note=(Microbial infection) In the presence of M: P61769; Host nucleus matrix : P12977
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 89859.75

構造登録者

Kjer-Nielsen, L.,Clements, C.S.,Brooks, A.G.,Purcell, A.W.,Fontes, M.R.,McCluskey, J.,Rossjohn, J. (登録日: 2002-06-11, 公開日: 2003-09-02, 最終更新日: 2017-10-11)

• 主引用文献: Kjer-Nielsen, L.,Clements, C.S.,Brooks, A.G.,Purcell, A.W.,Fontes, M.R.,McCluskey, J.,Rossjohn, J.; The structure of HLA-B8 complexed to an immunodominant viral determinant: peptide-induced conformational changes and a mode of MHC class I dimerization.; J.IMMUNOL., 169:5153-5160, 2003; PubMed: 12391232

実験手法

X-RAY DIFFRACTION (1.9 Å)