1M00

Rat neuronal NOS heme domain with N-butyl-N'-hydroxyguanidine bound

1M00 の概要

• エントリーDOI: 10.2210/pdb1m00/pdb
• 関連するPDBエントリー: 1LZX 1LZZ
• 分子名称: Nitric-oxide synthase, ACETATE ION, ZINC ION, ... (7 entities in total)
• 機能のキーワード: nitric oxide synthase, oxydoreductase, heme-enzyme, oxidoreductase
• 由来する生物種: Rattus norvegicus (Norway rat)
• 細胞内の位置: Cell membrane, sarcolemma; Peripheral membrane protein (By similarity): P29476
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 99271.75

構造登録者

Li, H.,Shimizu, H.,Flinspach, M.,Jamal, J.,Yang, W.,Xian, M.,Cai, T.,Wen, E.Z.,Jia, Q.,Wang, P.G.,Poulos, T.L. (登録日: 2002-06-11, 公開日: 2002-11-27, 最終更新日: 2024-02-14)

• 主引用文献: Li, H.,Shimizu, H.,Flinspach, M.,Jamal, J.,Yang, W.,Xian, M.,Cai, T.,Wen, E.Z.,Jia, Q.,Wang, P.G.,Poulos, T.L.; The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis; Biochemistry, 41:13868-13875, 2002; PubMed: 12437343; DOI: 10.1021/bi020417c

実験手法

X-RAY DIFFRACTION (2.05 Å)