1LVO

Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain

Summary for 1LVO

Entry DOI	10.2210/pdb1lvo/pdb
Descriptor	Replicase, hydrolase domain, SULFATE ION, 1,4-DIETHYLENE DIOXIDE, ... (5 entities in total)
Functional Keywords	3c like, corona, proteinase, chymotrypsin, cysteine histidine dyad, beta barrel, hydrolase
Biological source	Transmissible gastroenteritis virus
Total number of polymer chains	6
Total formula weight	202836.08
Authors	Anand, K.,Palm, G.J.,Mesters, J.R.,Siddell, S.G.,Ziebuhr, J.,Hilgenfeld, R. (deposition date: 2002-05-29, release date: 2002-07-17, Last modification date: 2024-03-13)
Primary citation	Anand, K.,Palm, G.J.,Mesters, J.R.,Siddell, S.G.,Ziebuhr, J.,Hilgenfeld, R. Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain. EMBO J., 21:3213-3224, 2002 Cited by PubMed: 12093723 DOI: 10.1093/emboj/cdf327 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation